For me, I use meclizine and it works great.

Melissa.

Thank you very much :) this will really help her out.

Is that the same as Dramamine?  (No sure of spelling...)  I get seasick, airsick, and I used to get carsick when I was little.  I HAVE to take Dramamine on flights or else I'll puke!  It knocks me out too, so I can go to sleep right away and not get scared as the plane takes off & gets turbulent.

No, they are not.

http://www.everydayhealth.com/health-questions/motion-sickness

Melissa.

Oh, I see, Melissa...Dramamine is dimenhydrinate. 

Miranda, tell your sister to use meclizine if she DOES NOT want to be drowsy. 

If she wants to sleep on the trip like me, then take dimenhydrinate :)

Meclizine makes me really tired also.

Melissa.